Platelet Delta granules storage pool deficiency in female patient with severe hemorrhagic syndrome

نویسندگان

چکیده

Introduction. Platelet dense granule disorders are a group of rare heterogeneous the blood coagulation system in which bleeding occurs due to functional and morphological platelet organelles accumulating phosphates bioactive amines. Aim — present clinical case 37-year-old patient with severe hemorrhagic syndrome. Basic information. An observation occurrence manifestations unspecified genesis is described. The results 25 healthy volunteer examinations both sexes were used as control for testing methods diagnosis disorder. Methods assessing hemostasis system, features using electron microscopy, well accumulation mepacrine flow cytometer studied. disorder was detected by microscopy confirmed cytometry manifestations, whom not verified prolonged period time.

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ژورنال

عنوان ژورنال: Gematologiia i transfuziologiia

سال: 2023

ISSN: ['0234-5730', '2411-3042']

DOI: https://doi.org/10.35754/0234-5730-2023-68-1-90-97